Student Scientific Journal

Review: Validation of Liquid Chromatography Analysis Methods for Anti-cancer Compounds

2023-10-18T02:19:18+00:00

Cancer is a disease with many variations and a high level of morbidity. Cancer therapy has significant development with the emergence of new anti-cancer compounds and using combinations of anti-cancer compounds. Therefore, a simple and appropriate analytical method is needed for the analysis of anti-cancer compounds in various sample forms. Liquid chromatography is a common method of analysis. This review will provide information on the validation of liquid chromatography analysis methods in the analysis of anticancer compounds. Parameters observed were linearity, accuracy and precision, sensitivity and specificity, and system suitability.

The Relationship between Knowledge and Attitude with the Implementation of Pregnant Gymnastics in Pregnant Women in Trisemester II and III at the Lubuk Linggau City Taba Health Center in 2023

2023-10-18T02:19:21+00:00

Pregnancy is the fertilization or union of a spermatozoa and an ovum followed by nidation or implantation. A normal pregnancy will last 40 weeks (10 lunar months or 9 months according to the international calendar). Pregnancy can be divided into 3 periods of approximately equal intervals (approximately 13 weeks or 3 months), which are known as trimesters I, II and III (Prawirohardjo, 2018). The purpose of the study was to find out the relationship between knowledge and attitudes with the implementation of pregnancy gymnastics in pregnant women in Trisemester II and III at the Lubuk Linggau City Taba Health Center in 2023 This type of research is analytical research using this type of research is analytical research using a cross-sectional design (Hidayat, 2012). The population in this study were all pregnant women in the second and third trimesters in the Taba health center area of Lubuk Linggau City in 2022, namely 391 people, the number of samples in this study were 80 respondents. The results of this study indicate that more than half of the respondents 42 (52.5%) were knowledgeable enough at Puskesmas Taba Lubuk Linggau City in 2023, most of the respondents 68 (85%) had a positive attitude at Puskesmas Taba Lubuk Linggau City in 2023, most of the respondents 70 (87.5%) did the implementation of pregnant gymnastics at Puskesmas Taba Lubuk Linggau City in 2023, There is a relationship between knowledge and the implementation of pregnant gymnastics at the health center taba lubuk linggau city in 2023, There is a relationship between attitudes and the implementation of pregnant gymnastics at the taba health center, Lubuk Linggau city in 2023 The results of this study are recommended to the health center to the health center to implement the pregnant gymnastics program, because pregnant gymnastics has many benefits for the health of pregnant women and smooth delivery and provide education about pregnant gymnastics.

Relationship between Knowledge, Immunization Status and Exclusive Breastfeeding History with the Incidence of Sickness in Toddlers at Puskesmas Sindang Beliti Ilir, Rejang Lebong Regency, 2023

2023-10-18T02:19:28+00:00

ARI is an infectious disease of the airway which is anatomically distinguished from the upper airway starting from the nose to the pharynx and the lower airway starting from the larynx to the alveoli and their adnexa which occurs due to the invasion of infecting agents which results in an inflammatory reaction of the airway involved (Lantong, et al, 2016 Research Objectives known relationship of knowledge, This type of research is an analytical study using a cross-sectional design which is a research design by measuring or observing at the same time (once at a time) between risk factors / exposure and disease (Hidayat, 2012). All mothers of toddlers who visited the Sindang Beliti Ilir health center in 2022 amounted to 349 people. and the number of samples in this study were 78 respondents. The results of this study indicate that half of the respondents 39 (50.0%) had good knowledge, almost all respondents 71 (91. 0%) Complete basic immunization status, almost all respondents 71 (91.0%), There is a history of exclusive breastfeeding, Most respondents 66 (84.6%) No URI, There is a relationship between knowledge and the incidence of URI (p value 0.044), There is a relationship between immunization status and the incidence of URI (p value 0.000), There is a relationship between exclusive breastfeeding history and the incidence of ARI (p value 0.000) at the Sindang Beliti Ilir Health Center, Rejang Lebong Regency in 2023.It is recommended that the results of this study to the health center will more often provide education to mothers who have toddlers, especially factors that can cause the incidence of ARI.

Factors associated with parents' decision to bring their children to the Ukp service of Muara Kulam Health Center, North Musi Rawas Regency in 2023

2023-10-18T02:19:33+00:00

Individual Health Efforts (UKP) or often called curative services, the target is individuals and or households. The orientation is the healing and rehabilitation of someone who falls ill. UPT Puskesmas Muara Kulam is an inpatient health center, which in its implementation implements programs both Public Health Service Efforts (UKM) and Individual Health Efforts (UKP). The utilization of basic health services by the community in 2020 was 45.8% of the 12,021 population.The purpose of this study was to determine the factors associated with the decision of parents to bring their children to the UKP service of the Muara Kulam Puskesmas, North Musi Rawas Regency in 2023.This type of research is analytical observational with a cross sectional design. The sample size of this study was 62 respondents selected by putposive sampling technique. The instrument used was a questionnaire. Data were analyzed using the chi-square test. The results showed that there was no relationship between age, education, employment, ownership of health insurance, availability of health workers and accessibility with the decision of parents to bring their children to the UKP Puskesmas Muara Kulam Mutara District. While for the perception of pain there is a significant relationship with a value of p=0.002. This study should be used as information and reference material to examine how to improve the utilization of health services at the puskesmas.

The Effect of Four Pillars Education on Diabetes Mellitus Disease on Self Efficacy at Rsud Rejang Lebong in 2023

2023-10-18T02:19:38+00:00

Based on data from the World Health Organization (WHO) in 2016, 70% of the total deaths in the world and more than half of the disease burden. 90-95% of Diabetes cases are Type 2 Diabetes which is largely preventable because it is caused by an unhealthy lifestyle (World Health Organization (WHO) Global Report, 2016). The research method carried out with a quasi-experimental research design (Quasi Experiment) with The One Group Pre-Post Test approach (The One Group Design), which is a research method carried out with the main objective of making a description or descriptive of a situation objectively (Notoatmodjo, 2010). The population in this study were patients with diabetes mellitus at Rejang Lebong Hospital in 2022, totaling 54 people, the number of samples in this study were 35 respondents. The results of this study showed that some respondents 19 (54.3%) before being given self efficacy education were not good at Rejang Lebong Hospital in 2023, most of the respondents 23 (65.7%) after being given good self efficacy education, there was an effect of four pillars education on diabetes mellitus disease on self efficacy at Rejang Lebong Hospital in 2023 (p value 0.017). The results of this study suggest that the RSUD can provide services by providing education, especially for patients with diabetes mellitus so as to increase self-efficacy.

The Relationship between Child Hospitalization Duration and Parent Anxiety Level at Rs Tiara Sella Bengkulu City 2023

2023-10-19T01:49:05+00:00

Children who are hospitalized will affect their physical and psychological state, this matter is called hospitalization (Apriany, 2018). Parents when children undergo hospitalization often experience anxiety due to stress. The problem of anxiety in parents if they do not have a good coping mechanism, can become severe anxiety or panic.Research Objectives The relationship between the length of hospitalization of children and the level of anxiety of parents at Tiara Sella Hospital Bengkulu Year 2023.This type of research is analytical research using a cross-sectional design which is a research design by measuring or observing at the same time (once in a while) between risk factors / exposure and disease (Hidayat, 2020). The population of this study was The population of this study were parents whose children underwent hospitalization totaling 120 people. the number of samples in this study was 55.The results of this study indicate that more than half of the respondents 30 (54.5%) stated that the length of stay was ≤ 5 days at Tiara Sella Hospital, Bengkulu City, 2023, Half of the respondents 28 (50.9%) stated mild anxiety at Tiara Sella Hospital, Bengkulu City, 2023, There is a relationship between the length of hospitalization of children and the level of anxiety of parents at Tiara Sella Hospital, Bengkulu City, 2023. The results of this study suggest that the Tiara Sella Hospital should pay more attention to the health status of children, not only physical problems but also their psychological adaptation in undergoing hospitalization in the hospital. The role of the hospital can be improved in one way such as: providing counseling for parents.

Relationship between demographic characteristics and length of illness with adherence of Dm Type Ii patients controlling blood sugar levels at Rsud Rupit, Muratara Regency, 2023

2023-10-19T01:52:15+00:00

Diabetes mellitus (DM) is often called the silent killer because this disease can affect all organs of the body and cause several kinds of complaints. The number of people with Diabetes Mellitus (DM) based on the province in South Sumatra is 5,220 people. The region with the most sufferers is Lubuk Linggau City with 1,176 DM sufferers. The purpose of this study was to analyze the characteristics and length of illness with the compliance of respondents to control blood sugar levels at Rupit Hospital, Muratara Regency. This type of research uses analytic observations with cross sectional methods. The sample in this study were type 2 DM patients as many as 42 samples. The sampling technique was carried out by purposive sampling, the researcher conducted an interview with the help of a questionnaire instrument. The dependent variable in this study was compliance with blood sugar control, while the independent variables were characteristics and length of illness. Data analysis using the Chi Square test. The results of the study showed that there was a relationship between age and education with respondents' compliance with controlling blood sugar levels (p = 0.000) and there was no relationship between work and length of illness with compliance with controlling blood sugar levels (p> 0.005). Based on this analysis, it can be concluded that there is a relationship between age and education with respondents' compliance in controlling blood sugar levels, and there is no relationship between work and length of illness with respondents' compliance in controlling blood sugar levels. The research suggestion is for the hospital to increase knowledge and information to patients with type 2 DM about the dangers posed by diabetes mellitus in the form of complications and how to handle them.

The Relationship between Mother's Role as Educator and Early Childhood Knowledge about Sex in the Working Area of Puskesmas Batu Bandung, Kepahiang Regency, 2023

2023-10-19T01:53:37+00:00

Sex education is still very taboo and is still considered not a topic of conversation that needs to be discussed with children. talk about sex is not an easy conversation for parents. Parents tend to avoid and close themselves about this topic by prohibiting children from asking and talking about sex. Based on the facts in the field, the level of sexual violence against children continues to increase every year. The purpose of this study was to identify the relationship between the role of mothers as educators with early childhood knowledge about sex in the working area of Puskesmas Batu Bandung in 2023.This type of research is analytical observational with cross sectional design. The number of samples of this study were 92 respondents selected by putposive sampling technique. The instrument used was a questionnaire. Data were analyzed using the chi-square test. The results showed that most of the respondents (72.8%) stated that their mothers acted as educators in early sex education, half of the respondents had good knowledge about early sex. The results of the Chi-Square test obtained p = 0.000 means that there is a relationship between the role of mothers as educators with early childhood knowledge about early childhood sex. This research should be used as information and reference material to examine how the role of parents in early childhood sex education.

The Relationship between Maternal Knowledge and Attitudes About Growth and Development with Maternal Behavior of Conducting Sdidtk in the Working Area of Puskesmas Tanjung Sakti Lahat Regency in 2023

2023-10-19T01:56:06+00:00

Children are the next generation of the nation, so the quality of the next generation depends on the quality of child development, especially in infants aged three years (toddlers), because the first three years of life. Monitoring the growth and development of toddlers is very important to determine the presence of growth disorders (growth faltering) early. To achieve effective interactions between mothers and children, mothers must pay attention to their attitudes because attitudes arise from interactions in understanding, feeling and behaving on an object that is valued positively and negatively.The purpose of this study was to determine the relationship between maternal knowledge and attitudes about child growth and development with maternal behavior of conducting SDIDTK in the Working Area of the Tanjung Sakti Health Center, Lahat Regency in 2023.This type of research is analytical observational with a cross sectional design. The number of samples of this study was 81 respondents selected by purposive sampling technique. The instrument used was a questionnaire. Data were analyzed using the chi-square test. The results showed that most respondents (63.4%) had good knowledge, supportive attitudes (70.4%) and good behavior (58%) towards the implementation of SDIDTK. There is a relationship between maternal knowledge and attitudes with maternal behavior to implement SDIDTK in children with a p value of 0.000. The results of this study should be used by the community as information material, and can provide knowledge about early detection of child growth and developmen

The Effect of Mini Modules on Parents' Knowledge of the Importance of Play Therapy in Toddlers During Hospitalization at Rsud Rupit Muratara Regency in 2023

2023-10-19T01:57:17+00:00

Hospitalization is a plan that requires children to stay in the hospital to undergo therapy and treatment. During this process children can experience traumatic and stressful. Most children who experience hospitalization show uncooperative behavior towards health workers shown by crying reactions. playing games will release children from the tension and stress they experience because by playing games, children will be able to divert their pain to the game. The type of research is Quasi Experimental, with a research design of One Group pre test and post test design. Sample 58 people. Structured mini-modules were given to every mother whose child was treated at Rupit Hospital. Questionnaires were given to respondents to assess the level of knowledge. Data analysis using Paired T-test parametric test. The average knowledge of respondents before being given a mini module is 54.7 and after being given a mini module to 71.21, with p < α = 0.05 with knowledge (p = 0.000). From these results it is concluded that there is an effect of giving mini modules about play therapy during hospitalization on knowledge. It is expected that the Rupit Hospital can provide a special room for play and play programs for children.

The Relationship between Maternal Characteristics, Toddlers and Compliance to the Posyandu with the Nutritional Status of Toddlers at the Padang Serai Health Center, Bengkulu City, 2023

2023-10-19T02:32:04+00:00

Toddlers are the age group that most often suffers from malnutrition and malnutrition, which can be assessed by measuring nutritional status. Nutritional status of toddlers is closely related to various factors including mother's age, mother's education level, parents' occupation, total family income, child characteristics and the regularity of mothers checking their children to the health service unit. This study aims to determine the relationship between the characteristics of mothers, toddlers and compliance to come to Posyandu with the nutritional status of toddlers at the Padang Serai Health Center, Bengkulu City in 2023.This research method is observational research using a cross sectional study approach and this research design is focused on knowing the factors of maternal characteristics, toddlers and compliance with coming to Posyandu that affect the nutritional status of toddlers with a total sample of 87 samples with a purposive sampling method then conducted interviews and filling out questionnaires by parents / mothers of toddlers and then measuring nutritional status based on anthropometric measurements of BB / UU compared to WHO_NCHS Z-score values. The results of the univariate test analysis of respondents who had toddlers with good nutritional status were 78 respondents (89.3%) while respondents who had toddlers with poor nutritional status were 9 respondents (10.3%). Bivariate analysis results There is no relationship between the characteristics of mothers, toddlers and the level of compliance of maternal visits to posyandu with the nutritional status of toddlers at the Padang Serai Health Center, Bengkulu City in 2023.Researchers suggest that the health center can provide useful information and input in efforts to improve health services for mothers and children, especially in providing counseling to mothers related to posyandu and nutritional status in toddlers.

Description The Knowledge And Willingness To Participate In The Covid-19 Vaccination In The Luwu Community

2023-10-19T02:37:22+00:00

At the end of 2019 a pandemic emerged from China in the city of Wuhan known as covid-19 which is a viral infectious disease caused by SARS-CoV (Severe Acute Respiratory Syndrome Corona Virus) which attacks the respiratory tract, this virus can spread quickly . Seeing a situation like this, the government has taken a policy by implementing social distancing recommendations and developing vaccines to prevent the wider spread of this pandemic. The purpose of this study was to describe the knowledge and willingness to participate in the covid-19 vaccination in the Luwu community. By using a descriptive survey method, sampling using a purposive sampling method with a total sample of 100 respondents. The results showed that the level of knowledge of the respondents 80% were in the very good category, 18% in the good category and a small part were in the fairly good category, namely 2%. And the level of willingness of most of the respondents are in the willing category as much as 50%. 48% are very willing and a small part are in the moderately willing category, namely as much as 2%. So from the results of this study it can be concluded that the picture of community knowledge is in the very good category (92%) and the picture of willingness is in the very willing category (78.8%).